neurofibrillary tangles meaning in English
神经原纤维缠结
Examples
- Upon autopsy , the presence of amyloid plaques and neurofibrillary tangles is used to positively diagnose alzheimer ' s disease
经过尸体解剖，淀粉质色斑的出现和神经原纤维的混乱状态被用来确诊阿兹海默症。 - In alzheimer ' s disease brain cells degenerate , brain mass shrinks and characteristic neurofibrillary tangles and neural plaques are seen post mortem
而在早老性痴呆症患者死亡后检验发现有脑细胞退化、脑组织缩小、典型的神经原纤维纠结及神经斑块等现象。 - To his surprise , barrio found that fddnp had a specific affinity for the neurofibrillary tangles and beta - amyloid plaques found in the brains of alzheimer ' s patients
令barrio吃惊的是，他发现fddnp对阿尔茨海默病患者脑中的神经纤维团和-淀粉样蛋白斑有特别的亲和性。 - Lewy body disease that is quite common in the west , is not commonly encountered . in alzheimer s disease brains in chinese , amyloid deposition predominantes whereas neurofibrillary tangles are less frequently seen
在病种方面，以阿氏痴呆症为主，约占23 ，脑血管性痴呆占13 ；而在西方很常见的路易体痴呆病则非常罕见。 - It may have a preventional function from alzheimer ' s disease . molecular biological studies are shown that apoe isoform has a isoform - specific role to neurodegeneration . apoe3 and apoei aid to sustain the stabilization of cytoskeleton protein tau , while apoe4hyperphosphorylates tau to destabilize the microtubule protein , which will make neurocyte easy to form neurofibrillary tangles in ad
分子生物学研究发现， apoe异构体对神经细胞退化表现出异构体特异作用， apoe _ 3和apoe _ 2有助于维持微管的稳定性，而apoe _ 4则使tau蛋白超磷酸化，破坏微管的稳定性，使神经细胞易于形成神经纤维缠结。